Daniel Cole was in Plymouth before 1640, when he had a large tract of land granted to him at Duxbury. He was in Marshfield by 1642, then at Yarmouth, then finally at Eastham by 1649. In that year he sold his land at Duxbury to Edmond Weston.
Daniel was an active and respected citizen. He served as Deputy to the General Court, representing Eastham for a number of years, was a Selectman, Town Clerk, grand juror, and constable. He also was appointed to purchase on behalf of Gov. Thomas Prence a place at Plain Dealing in Plymouth, which had been selected for the residence of the Governor. He was a member of the grand inquest to hear the indictment against Alice Bishop who was charged with murdering her child and was on the coroner's jury that found that Daniel Doane's child accidentally drowned in a well.
Mr. Cole, Mr. Thomas Prence and Mr. John Freeman were appointed by the town to use their "best endeavors to put forward or encourage the Indians" or the "English to kill the wolves."
He was a tailor by trade in England. In 1661 Daniel Cole had liberty granted him to "draw and sell strong water and wine at Eastham, provided that he always be furnished with good wine for the supply of those that are in need amongst them." Only men of character were allowed to sell liquor at this time. It was a lucrative business, and large amounts were consumed, so men of less character would water the liquor down, something the government wanted to avoid.